Stress and pore pressure histories in complex tectonic settings predicted with coupled geomechanical-fluid flow models

Most of the methods currently used for pore pressure prediction in sedimentary basins assume one dimensional compaction based on relationships between vertical effective stress and porosity. These methods may be inaccurate in complex tectonic regimes where stress tensors are variable. Modelling approaches for compaction adopted within the geotechnical field account for both the full three dimensional stress tensor and the stress history. In this paper a coupled geomechanical-fluid flow model is used, along with an advanced version of the Cam-Clay constitutive model, to investigate stress,pore pressure and porosity in a Gulf of Mexico style mini-basin bounded by salt subjected to lateral deformation. The modelled structure consists of two depocentres separated by a salt diapir. 20% of horizontal shortening synchronous to basin sedimentation is imposed. An additional model accounting solely for the overpressure generated due to 1D disequilibrium compaction is also defined. The predicted deformation regime in the two depocentres of the mini-basin is one of tectonic lateral compression, in which the horizontal effective stress is higher than the vertical effective stress. In contrast, sediments above the central salt diapir show lateral extension and tectonic vertical compaction due to the rise of the diapir. Compared to the 1D model, the horizontal shortening in the mini-basin increases the predicted present-day overpressure by 50%, from 20 MPa to 30 MPa. The porosities predicted by the mini-basin models are used to perform 1D, porosity-based pore pressure predictions. The 1D method underestimated overpressure by up to 6 MPa at 3400 m depth (26% of the total overpressure) in the well located at the basin depocentre and up to 3 MPa at 1900 m depth (34% of the total overpressure) in the well located above the salt diapir. The results show how 2D/3D methods are required to accurately predict overpressure in regions in which tectonic stresses are important

Catalog of Nearby Isolated Galaxies in the Volume z<0.01

We present a catalog of 520 most isolated nearby galaxies with radial velocities V_LG<3500 km/s covering the entire sky. This population of "space orphans" makes up 4.8% among 10900 galaxies with measured radial velocities. We describe the isolation criterion used to select our sample, called the "Local Orphan Galaxies" (LOG), and discuss their basic optical and HI properties. A half of the LOG catalog is occupied by the Sdm, Im and Ir morphological type galaxies without a bulge. The median ratio M_gas/M_star in the LOG galaxies exceeds 1. The distribution of the catalog galaxies on the sky looks uniform with some signatures of a weak clustering on the scale of about 0.5 Mpc. The LOG galaxies are located in the regions where the mean local density of matter is approximately 50 times lower than the mean global density. We indicate a number of LOG galaxies with distorted structures, which may be the consequence of interaction of isolated galaxies with massive dark objects

Whole-genome sequencing reveals host factors underlying critical COVID-19

Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2,3,4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes—including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)—in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease

Macrobenthic migration and its influence on the intertidal diversity dynamics of a meso-tidal system

The link between movement and migration of organisms to patterns of biodiversity may be an important mechanism of biodiversity maintenance at local scales. but is regularly underestimated in marine studies. Patterns of diversity, density and distribution of all mobile macrofaunal components of an intertidal assemblage were quantitatively investigated throughout diurnal and tidal cycles In a meso-tidal system southwest Ireland. A significant trend of decreasing diversity with shore height was observed during periods of emersion at both day and night, but not during immersion. While certain taxa (e.g. the isopod Ligia oceanica and the sea mite Erythraeus sp.) exhibited obvious patterns of activity and migration with tide and time, the majority of species were observed to be sedentary or showed no obvious pattern of migration. The influence of rare, transient species on biodiversity measurement and community structure was significant, particularly during periods of immersion. In order to produce meaningful descriptions of intertidal biodiversity, it is therefore crucial that future studies be conducted during periods of immersion and emersion, and that they should consider the influence of migrating species

A diagenesis model for geomechanical simulations: formulation and implications for pore pressure and development of geological structures

Forward basin modelling is routinely used in many geological applications, with the critical limitation that chemical diagenetic reactions are often neglected or poorly represented. Here, a new, temperature‐dependent, kinetic diagenesis model is formulated and implemented within a hydromechanical framework. The model simulates the macroscopic effects of diagenesis on: 1) porosity loss, 2) sediment strength, 3) sediment stiffness and compressibility, 4) change in elastic properties, 5) increase in tensile strength due to cementation and 6) overpressure generation. A brief overview of the main diagenetic reactions relevant to basin modelling is presented and the model calibration procedure is demonstrated using published data for the Kimmeridge Clay Formation. The calibrated model is used to show the implications of diagenesis on prediction of overpressure development and structural deformation. The incorporation of diagenesis in a uniaxial burial model results in an increase in overpressure of up to 9 MPa due to both stress‐independent porosity loss and overpressure generated by disequilibrium compaction caused by a reduction in permeability. Finally, a compressional model is used to show that the incorporation of diagenesis within geomechanical models allows the transition from ductile to brittle behaviour to be captured due to the increase in strength that results in an over‐consolidated stress state. This is illustrated by comparison of the present day structures predicted by a geomechanical‐only model, where a ductile fold forms, and a geomechanical model accounting for diagenesis in which a brittle thrust structure is predicted

Assessing the implications of tectonic compaction on pore pressure using a coupled geomechanical approach

Overpressure prediction in tectonic environments is a challenging topic. The available pore pressure prediction methods are designed to work in environments where compaction is mostly one dimensional and driven by the vertical effective stress applied by the overburden. Furthermore, the impact of tectonic deformation on stresses, porosity and overpressure is still poorly understood. We use a novel methodology to capture the true compaction phenomena occurring in an evolving 3D stress regime by integrating a fully-coupled geomechanical approach with a critical state constitutive model. To this end, numerical models consisting of 2D plane strain clay columns are developed to account for compaction and overpressure generation during sedimentation and tectonic activity. We demonstrate that a high deviatoric stress is generated in compressional tectonic basins, resulting in a substantial decrease in porosity with continuing overpressure increase. The overpressure predictions from our numerical models are then compared to those estimated by the equivalent depth method (EDM) in order to quantify the error induced when using classical approaches, based on vertical effective stress, in tectonic environments. The stress paths presented here reveal that a deviation from the uniaxial burial trend can substantially reduce the accuracy of the EDM overpressure predictions

Integrating petrophysical, geological and geomechanical modelling to assess stress states, overpressure development and compartmentalisation adjacent to a salt wall, gulf of Mexico

Multi-well pressure data from the Magnolia Field, located on a flank of the salt-bounded Titan passive mini-basin in the Garden Banks area of the continental slope of the Gulf of Mexico, indicate remarkably high overpressures that vary, at similar depths, by up to 10 MPa between sand bodies 1 km apart. In the present paper, we integrate geological and geophysical analysis with 2D forward hydro-mechanical evolutionary modelling to assess the contribution of both disequilibrium compaction and diapir-related tectonic loading to the observed overpressure and to understand controls on pressure compartmentalisation. The 2D finite element evolutionary model captured the sedimentation of isolated sand channels bounded by mud-dominated sediments close to a rising salt wall which led to tectonic loading on sediments. Comparison of results from the 2D and 1D models shows that disequilibrium compaction can explain most of the overpressure as a result of very rapid deposition of mainly mud-rich, low permeability sediments; tectonic loading contributes around 7% of the observed overpressure. The models also show that linked to the high sedimentation rates, small variations in the permeability and connectivity of the mud-rich sections that bound the channel sands result in highly compartmentalised pressure distributions in adjacent sand bodies